Increasing evidence suggests that numerous m6A targets contribute to tumorigenesis, including Snail, CTNNB1, NANOG, APC, and genes associated with the Akt/mTOR pathway [11, 25–28] However, conflicting reports have indicated that METTL3 may function as a tumor suppressor in certain tumor types. The gene discussed is METTL3; the disease is neoplasm.