The results showed that the pathways enriched by GO in APOL6 gene were defense response PRESESE virus, response to virus and other pathways (Fig. 9A), KEGG enriched pathways were antigen PRESESSING and PATNTATION, glycerophospholipid metabolism and other pathways (Fig. 9B); GO enriched pathways of HOXC6 gene include exploration behavior, muscle fiber development and other pathways (Fig. 9C), while KEGG enriched pathways include ecm receptor interaction, dilated cardiomyopathy and other pathways(Fig. 9D). The gene discussed is HOXC6; the disease is dilated cardiomyopathy.