Furthermore, immunohistochemical staining revealed that PLS3 was strongly expressed on the tumor cell-surface in 17 of 35 PTCLs (10 of 20 angioimmunoblastic T-cell lymphomas, 2 of 5 nodal PTCLs with TFH phenotypes, and 5 of 10 PTCLs not otherwise specified), accounting for 48.6% PTCL samples examined, while significant expression was observed in only one of 168 (0.6%) mature B-cell lymphomas (Fig. 4C; Table S10). The gene discussed is PLS3; the disease is angioimmunoblastic T-cell lymphoma.