Tumor cell infiltration was also identified in 12 of 16 PB samples (0.24–74.0% in PB MNCs; Table S4), five of which showed expansion of single-chain TCR tumor cells with CD3ε- CD4+ PD1high T-cell populations by FCM, consistent with the LN data (Fig. S2F and S3A–C). The gene discussed is CD4; the disease is neoplasm.