Additionally, we could confirm the upregulation and zonation of Vcam1|Itgb1 and Ccl3|Ccr5 in NAFLD livers, suggesting that upregulation of these ligands and receptors is a response to inflammatory liver perturbations in general (Supplementary Fig. 4g, h). The gene discussed is CCL3; the disease is metabolic dysfunction-associated steatotic liver disease.