INS and type 2 diabetes mellitus: CCR5+M are related to neuroinflammation (Ubogu et al., 2006) and insulin insensitivity (Blanks et al., 2020), therefore the greater adhesion capacity of CCR5+M in SAs with central obesity provides insight as to why SAs have higher type 2 diabetes risk compared with WEs for any given BMI (Sattar & Gill, 2015).