Following expression as surface glycoproteins, the ectodomains of UL7, UL8, and UL10 can be released into the supernatant following proteolytic cleavage, although in the case of UL7 and UL8 this is prevented during infection because HCMV inhibits the activity of the metalloprotease responsible (ADAM17) (74). Here, RPLP0 is linked to infection.