CoCuLncSig correlated with some of the tumor immune cycle steps, which the top 10 ranked were Step 4 CD4 T cell recruiting, Step 4 Basophil recruiting, Step 4 Eosinophil recruiting, Step 5 Infiltration of immune cells into tumors, Step 2 Cancer antigen presentation, Step 4 TH17 cell recruiting, Step 4 MDSC recruiting, Step 4 Neutrophil recruiting, Step 1 Release of cancer cell antigens, and Step 4 B cell recruiting (Figure 7B, Supplementary Table 6). The gene discussed is CD4; the disease is cancer.