LRRK2 and Platelet storage pool disease: E. coli strains (NRG 857C and HM427) were isolated from the fecal suspension of sPD patients, and were regularly gavaged together to Lrrk2 transgenic mice (Lrrk2RP/+ PD-E. coli, Lrrk2RP/RP PD-E. coli) every 3 weeks for 10 weeks.