Both of these two diseases are chronic progressive diseases which may share common pathophysiological links.18 Increasing studies have noted that intestinal microbiota dysbiosis is likely to sustain mucosal inflammation and hasbeen linked to increased risk for sPD and CD.43,44 However, few studies have characterized the intestinal microbiota composition of patients with LRRK2-associated sPD. This evidence concerns the gene LRRK2 and Platelet storage pool disease.