PLIN2 and neoplasm: Interestingly, top differentially expressed genes between aGvHD and healthy skin MNPs included MT2A (encoding metallothionein-2), a gene upregulated in tissue repair MΦ,27TIMP1, which regulates the angiogenetic capacity of MΦs28 and PLIN2, a gene involved in lipid storage, which is expressed by immunosuppressive tumour-associated MΦs (Figure S4b).29