Indeed, post-infection time-course RNA-seq analysis showed an upregulation of Casp3 but also a number of other genes involved in apoptosis and necroptosis such as Stk24, Akt1, Madd, Casp7, and Casp8 peaking at 5 and 6 dpi (Fig. 4f). The gene discussed is CASP7; the disease is infection.