RIPK3 and Splenomegaly: By crossing RIPK3‐knockout mice with Abin1Q478H/Q478H mice, we generated Abin1Q478H/Q478HRipk3–/– mice, which displayed increased RBC and hemoglobin levels (Figure 5a) as well as alleviated splenomegaly compared with Abin1Q478H/Q478H mice (Figure 5b).