However, the known functions of ABIN1 are currently limited to its role in controlling mouse embryonic development through the regulation of TNF signaling as well as its involvement in the regulation of autoimmunity via TLR–MyD88.[9, 10, 17] Therefore, the specific role of ABIN1 in hematopoiesis remains unclear and requires further investigation. The gene discussed is TNF; the disease is Autoimmunity.