Necroptosis‐independent RIPK3 function contributes to anemia, while co‐deletion of Ifnar1 rescues anemia, thrombocytopenia, and splenomegaly, highlighting ABIN1 (Q478) as a regulator of hematopoietic deficiencies through type I IFN expression. The gene discussed is IFNAR1; the disease is anemia (phenotype).