Our previous studies showed that the clinically used lysosomotropic drug chloroquine (CQ) exerted antimetastatic effects in melanoma by primarily normalizing the tumor vasculature through enhanced Notch signaling (Maes et al, 2014), but the effects of CQ on NF‐κB signaling in TECs were not explored. The gene discussed is NFKB1; the disease is neoplasm.