CD31/AQP1 double‐positive (identifying huTECs), CD8+ PD1− GrzB− T‐cells (identifying naïve CD8+ T‐cells) and CD8+ PD1+ GrzB+ (identifying activated/effector CD8+ T‐cells) (Sade‐Feldman et al, 2018) were evaluated in three distinct spatial compartments of the biopsy, namely the “tumoral bulk,” the tumor–stroma interface, and the nontumoral areas. This evidence concerns the gene PECAM1 and neoplasm.