MIR34A expression resulted in downregulation of the stemness factors BMI1 proto-oncogene polycomb ring finger (BMI1), CD44, CD133, olfactomedin 4 (OLFM4), and MYC proto-oncogene bHLH transcription factor (MYC) in a colon cancer cell line[95], clearly connecting this axis to stemness. The gene discussed is OLFM4; the disease is colonic neoplasm.