CTNNB1 and endometrial carcinoma: Abnormal expression of β-catenin in cells also affects migration and cell invasion, and it arises from the disruption of the gene associated with β-catenin (specifically Catenin Beta-1/CTNNB-1) which plays a significant role in endometrial carcinoma progression [11] Moreover, nuclear expression of β-catenin was more frequent in endometrioid adenocarcinoma [12].