NLK and colorectal carcinoma: Our results showed the related genes of Wnt/β-catenin signaling pathway, such as β-catenin, GSK-3β, c-myc, and EMT-related proteins were affected by circ_0009092/miR-665/NLK, indicating circ_0009092/miR-665/NLK inhibits Wnt/β-catenin signaling pathway and suppresses EMT progression in CRC.