Interestingly, compared to other similar gene expression studies15,27, the candidate markers of LC found in our study (ANXA3, ARG1 and HP) were observed significantly upregulated (FDR < 1.55E-04) in a lung cancer subtype defined as ‘LC2’ compared to healthy controls in the study performed by Zhang and colleagues15 (with logFC values 0.69, 0.79 and 1.38, respectively). The gene discussed is HP; the disease is lung carcinoma.