ANXA3 and lung cancer: Interestingly, compared to other similar gene expression studies15,27, the candidate markers of LC found in our study (ANXA3, ARG1 and HP) were observed significantly upregulated (FDR < 1.55E-04) in a lung cancer subtype defined as ‘LC2’ compared to healthy controls in the study performed by Zhang and colleagues15 (with logFC values 0.69, 0.79 and 1.38, respectively).