Parabacteroides, Faecalibacterium, Bacteroides, and unclassified Lachnospiraceae were positively correlated with the homeostasis model assessment of β-cell function (HOMA-β) but negatively correlated with the homeostasis model assessment measure of insulin resistance (HOMA-IR), insulin, fasting blood glucose (FBG), and glycated hemoglobin (HbA1c) levels (Fig. 1g). The gene discussed is INS; the disease is Insulin resistance.