BRCA1 and twin to twin transfusion syndrome: Moreover, three smaller clusters were also significant, which detected whether epigenetically modified breast cancer-related BRCA1 loci moonlights as a potential CVD biomarker (cluster #10, “brca1”) [63], investigated the long-term effects led by fetal programming on the cardiovascular health outcomes in adulthood of infants surviving from twin-twin transfusion syndrome (TTTS) (cluster #13, “twin-twin transfusion syndrome”) [64] and focused on the unique epigenetic mechanisms underpinning the cardioprotective property of dexmedetomidine (Dex) (cluster #14, “dex”) [65], respectively.