RBFOX2 and type 2 diabetes mellitus: We further investigated the correlation of alternative splicing events at the exon level and observe that there are a subset of alternative splicing events, shared between the Rbfox2-KD β cells and Rbfox2-mut islets (Fig. S5C), as well as the Rbfox2-mut islets and T2D islets (Fig. S5D).