Later, this study group investigated SECISBP2 that regulates GPX4 translation in 165 DLBCL patients treated with R-CHOP, and HADHB involved in fatty acid beta oxidation in 128 DLBCL patients (treatment unknown), and also found significant unfavorable prognostic effects in DLBCL [133, 134] (Table 2). This evidence concerns the gene SECISBP2 and diffuse large B-cell lymphoma.