It has been proposed that Clec7a, a member of the C-type lectin receptor (CLR) family that encodes the dectin1 protein and recognizes β-glucans at fungal cell walls [20], might be a key factor in the development of fungus-associated obesity, as Clec7a expression was upregulated in adipose tissues, while dectin-1 antagonist treatment was observed to improve glucose homeostasis [20]. This evidence concerns the gene CLEC7A and obesity due to melanocortin 4 receptor deficiency.