At present, domestic and foreign studies have confirmed that circRNA can participate in the occurrence and development of laryngeal squamous cell carcinoma,8 bladder cancer,9 breast cancer,10 etc. In Non-Small Cell Lung Cancer (NSCLC), highly expressed circ_ZNF124 promotes the occurrence and development of NSCLC by promoting the activation of JAK2/STAT3 signaling pathway.11 This evidence concerns the gene STAT3 and non-small cell lung carcinoma.