IBSP and osteosarcoma: The univariate and multivariate analysis confirmed that IBSP expression was an independent risk factor for OS (HR = 3.425, 95% CI: 1.604–7.313, P = 0.002) and RFS (HR = 3.377, 95% CI: 1.775–6.424, P < 0.001) in osteosarcoma patients.