ALB and obesity due to melanocortin 4 receptor deficiency: Mejia-Vilet [11] proposed nine parameters, that predicted up to 99% of ICU hospital admission: male gender, obesity (Body Mass Index, BMI ≥ 30 kg/m2), systolic blood pressure < 100 mmHg, Charlson index ≥ 3, glucose > 200 mg/dL, albumin < 3.5 mg/dL, lactate dehydrogenase (LDH) > 474 U/L, SaO2/FiO2 ratio < 300, and lung damage > 50%.