There is evidence of a correlation between the virome and 548 host genes at FDR < 1, representing multiple pathways related to immune response and infection, including toll-like receptor 2 (TLR2); CD4 molecule (CD4); interleukin 2 receptor gamma subunit (IL2RG); interleukin 6 receptor (IL6R); interleukin 3 receptor alpha subunit (IL3RA) and major histocompatibility complex, class II; DM beta (HLA-DMB); major histocompatibility complex, class II; DP alpha 1 (HLA-DPA1); and major histocompatibility complex, class II, DR alpha (HLADRA) genes [119]. Here, CD4 is linked to infection.