Similarly, for IRF3 phosphorylation (Figure 7E), both the viral infection with Cyclo (Phe-Pro) and the 6.25 μg/mL naringenin group with Cyclo (Phe-Pro) added to the viral infection significantly elevated the phosphorylation level of IRF3 compared with the viral infection group. The gene discussed is IRF3; the disease is viral infectious disease.