A study demonstrated that anthocyanins from black rice, black soybeans, and purple corn alleviated oxidative stress and inflammation-related obesity in HF-diet-induced mice by suppressing the expression of TNFα, IL-6, inducible nitric oxide synthase (iNOS), and NF-κB, and increasing the hepatic superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities [82]. The gene discussed is NOS2; the disease is obesity due to melanocortin 4 receptor deficiency.