INS and diabetes mellitus: The International Hypoglycemia Study Group, who focus primarily on the use of CGM and other metrics in diabetes, have recently stated that a threshold of blood or interstitial glucose of <54 mg/dL (<3.0 mmol/L), which is thought to be rare in people who are not on insulin therapy, or on an insulin secretagogue, should be used when reporting on Level 1 “clinically important hypoglycemia” (i.e., impairs cognition, promotes cardiac arrhythmia, etc.), while values >53 mg/dL but <70 mg/dL are to be considered Level 1 hypoglycemia “alerts” [31].