ACHE and Alzheimer disease: Quercetin can act on different general mechanisms of AD etiology in a variety of in vitro and in vivo models, such as protecting neuronal cells by attenuating oxidative stress and neuroinflammation [16,17], inhibiting Aβ aggregation and tau phosphorylation [18,19], and restoring cholinergic function (acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition) [20].