BCL2 and non-small cell lung carcinoma: Its antitumor ability is hundreds of times stronger than that of existing antitumor drugs [92].Cryptophycin-52 not only has microtubule inhibition activity but also showed the ability to induce apoptosis by Bcl-2 phosphorylation in the human H460 non-small-cell lung carcinoma (NSCLC) cell line [93].