QCT regulates the activation of Caspase 3, Caspase 8, Caspase 9, and p53 phosphorylation, and it inhibits STAT3 signaling, the PI3K/AKT survival pathway, and the MAPK and NF-κB pathways, which are crucial in cancer development and progression [92]. The gene discussed is CASP3; the disease is cancer.