It is noteworthy that Chen et al. reported a trend of association between the carriers of the TYMP rs11479-T allele and a higher incidence of HFS (p = 0.092) and grade 2 anemia (p = 0.056), indicating that the T allele carriers of this SNP may be more sensitive to capecitabine compared to C allele carriers [56]. The gene discussed is TYMP; the disease is Hand-foot syndrome.