The prognostic value of pyroptosis-related genes with the top eight HR values in GBM patients in the high-/low-expression groups was 5.18 for CASP6, 5.17 for GBP1, 4.73 for CASP8, 4.24 for CASP4, 4.1 for GBP5, and 4.07 for GSDMD (Figure 2). This evidence concerns the gene CASP4 and glioblastoma.