The LASSO Cox regression model of six pyroptosis-related genes (CASP6, CASP8, CASP4, GBP1, GBP5, and GSDMD) was built to accurately and conveniently predict the 1-, 2-, and 3-year overall survival rates of GBM patients based on the dataset from TCGA. Here, GBP5 is linked to glioblastoma.