In a sepsis mouse model, FMT can regulate the abundance of bacteria such as Firmicutes, Proteobacteria, Escherichia Shigella, and Lactobacillus to a level comparable to that of healthy mice, and downregulate the expression of the NOD-like receptor protein 3 (NLRP3) and Gasdermin-D (GSDMD)-N proteins and the release of inflammatory factors to inhibit cell pyroptosis [53]. This evidence concerns the gene GSDMD and Sepsis.