IGHE and asthma: The administration of a combination of biologics, concurrently or sequentially, was decided by the authors of the included articles following inflammation biomarkers (i.e., blood eosinophils, FeNO, serum IgE levels) when severe asthma was uncontrolled on a biologic monotherapy and according to patient comorbidities when the patient was affected by severe asthma and another T2 condition eligible for biologic treatment.