GWAS in critical patients with COVID-19 recruited from GenOMICC (Genetics Of Mortality In Critical Care) from 208 intensive care units in the United Kingdom showed that A allele of rs2236757 in IFNAR2 was associated (p = 4.9 × 10−8, OR = 1.28) with needing mechanical ventilation, supplementary oxygen, or having pneumonia associated to COVID-19. This evidence concerns the gene IFNAR2 and COVID-19.