Similarly, the administration of autophagy-inducing compounds like NAD+, Rap, and carbamazepine, which activate autophagy either through mTOR-dependent or -independent pathways, has demonstrated the ability to prevent memory loss and rescue cognitive deficits in both Aβ and Tau C. elegans and mouse models of AD [33,34,35]. Here, LRPAP1 is linked to Alzheimer disease.