AKT1 and cancer: Meanwhile, CPT1A also shares multiple connections with many other cellular signaling pathways, including c-MYC or AMPK in breast cancer, and promotes cancer proliferation, metastasis or therapeutic resistance through several oncogenic signaling pathways, such as PI3K/AKT/mTOR, VEGF, ERK and Src pathways [23,24,25,26,27,28].