Our preliminary functional analyses measuring the effects of suppressing CDH3 expression following unspecific endogenous re-expression induced by exposure of the various cancer cell models to 5-AZA indicated that changes in CDH3 expression might be associated with changes in cell invasiveness, as two RCC and one bladder cancer cell line models exhibited altered mobility when migrating through a Matrigel barrier in the real-time impedance analysis. Here, CDH3 is linked to urinary bladder carcinoma.