For group 2, the loci-related genes HLA-DPA2, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DQB3, and COL11A2P1, were determined to be associated with HCC in the Taiwanese patients enrolled in this study but not in the UK Biobank and BBJ participants. The gene discussed is COL11A2P1; the disease is hepatocellular carcinoma.