Mposhi et al. further functionally confirmed these findings by bisulfite pyrosequencing, qPCR, and nanopore-episequencing approaches in a mouse model and in transgenic steatosis HepG2 cell models with mitochondrial overexpression of CpG (MSssI) or GpC (MCviPI)-specific DNA methyltransferases, which similarly revealed evidence for MASH-specific lipid metabolic changes in gene expression [21]. Here, GYPC is linked to steatosis.