Predicted functional pathway analysis of the DE miRNAs in both 8-week and 16-week T. forsythia-infected mice identified several pathways (DIANA-miRPath): Mitogen-activated protein kinase (MAPK) signaling pathway, transforming growth factor (TGF)-β, Wnt (Wingless and Int-1), and signaling pathways related to various cancers such as pancreatic cancer and prostate cancer (Figure 2C). Here, WNK2 is linked to familial pancreatic carcinoma.