The upregulation of SH3PXD2A-AS1 was found to promote HaCaT cell proliferation and supress HaCaT cell apoptosis, participating in the STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop which affects the pathogenesis of psoriasis [44]. This evidence concerns the gene STAT3 and psoriasis.