CFTR and Infertility: Solovyova et al. (2018) analyzed the CFTR gene in 2146 Russian men from infertile couples, and detected the R117H variant in 8 patients, including four compound-heterozygous F508del/R117H; 9T/7T (azoospermia, n = 4); and four heterozygous R117H/N; 7T/7T (azoospermia, n = 3; oligozoospermia, n = 1) [24].