Detailed genotype–phenotype correlations in patients with SCN8A mutations have been presented in six different clinical groups: BFNIE with normal cognition and pharmacoresponsive seizures, intermediate epilepsy with mild intellectual disability and partial pharmacoresponsiveness, DEE with severe intellectual disability and mostly pharmacoresistant seizures, generalized epilepsy with mild to moderate intellectual disability and absence seizures, unclassifiable epilepsy, and mild to moderate neurodevelopmental disorders without epilepsy. Here, SCN8A is linked to juvenile absence epilepsy.