Although IL-13 hardly emerged as a good biomarker in glioblastoma (AUC = 0.536, specificity 85%, sensitivity 38%, RR = 0.459, 95%CI 0.213–0.888), its diagnostics usefulness increased in NLR + IL-13 model to AUC = 0.830 and classifier accuracy >80%. Here, IL13 is linked to glioblastoma.