The comparison of patients with GBM according to the cut-off value of 63 years established in our previous studies showed significantly lower levels of TNFα (51.35 ± 26.97 pg/mL) in patients aged ≤63 years than in patients aged >63 years (62.53 ± 16.76 pg/mL) [12]. This evidence concerns the gene TNF and glioblastoma.