Thus, our data bode well for linking gene activity changes to tumor progression and metastasis, suggesting that, (a) TGFβ1’s elevated activity aligns with invasion promotion, (b) ROAR’s surge suggests heightened invasiveness, (c) DAB2’s rise echoes invasion dynamics, (d) BMP6’s elevation points to tumor progression, (e) NOS2’s increase connects to invasiveness, (f) PLXN2’s upregulation implies migration involvement and, (g) CADPS’s rise aligns with invasiveness [63,64,65,66,67,68,69]. The gene discussed is PLXNA2; the disease is neoplasm.