Canonical KEGG pathway analyses indicated that the differentially expressed miRNAs were involved in MAPK signaling (p = 3.03 × 10−5), insulin secretion (p = 3.7 × 10−4), the PI3K-Akt signaling pathway (p = 8.9 × 10−4), adrenergic signaling in cardiomyocytes (p = 0.005), choline metabolism in cancer (p = 0.004), neurotrophin signaling (p = 0.005), gastric cancer (p = 0.005), melanoma (p = 0.01) and non-small cell lung cancer (p = 0.01) (Figure 6g). Here, INS is linked to melanoma.