PROS1 and COVID-19: We identified several Omicron (BA.1) subvariants (BA.2, BA.2.12.1, BA.4/BA.5, BA.2.75, BA.2.75_K147E, BA.4.6 and BA.4.6_N658S) by whole-genome sequence analysis of the SARS-CoV-2 S protein isolated from COVID-19 patients in South Korea.