In a study involving 85 patients who experienced myopathy while being treated with a daily dose of 80 mg of simvastatin, along with 90 control subjects who did not develop myopathy, researchers analyzed approximately 300,000 genome markers, discovering a noncoding SNP within the SLCO1B1 gene in nearly complete linkage disequilibrium with the c.521T>C SNP, showing a significant association with myopathy at a genome-wide significance level [58,59]. The gene discussed is SLCO1B1; the disease is myopathy.